Sermorelin & GHRP-2 Blend (10mg)

Buy Sermorelin GHRP-2 Blend – Advanced Peptide for Growth Hormone Research

The Sermorelin & GHRP-2 peptide blend is a specialized research tool designed for laboratory studies focused on growth hormone (GH) release and IGF-1 signaling. By combining a GHRH analog with a potent GH secretagogue, this blend enables researchers to explore dual-receptor activation in pituitary somatotrophs.

Sermorelin, a 29-amino acid analog of endogenous GHRH, primarily activates GHRH receptors, stimulating intracellular cAMP pathways that drive GH synthesis. GHRP-2, a synthetic hexapeptide, targets GHS-R1a receptors (ghrelin-sensitive), triggering PLC, IP₃, DAG, and PKC pathways to release GH.

How the Blend Works

• Sermorelin: Activates GHRH receptors to initiate growth hormone synthesis.
• GHRP-2: Targets ghrelin receptors to produce high-amplitude GH secretion bursts.
• Synergy: Dual receptor activation may amplify GH release beyond individual peptides, producing a measurable increase in IGF-1 levels.

Research Insights

• Sermorelin can double GH output in 12-hour pituitary cell assays.
• GHRP-2 may raise GH levels 4–6 fold over baseline, supporting sustained IGF-1 elevation by 50–80%.
• Combined, these peptides show synergistic effects, increasing GH release significantly more than either peptide alone.
• Laboratory studies suggest potential secondary effects on other cell types, such as increased IGF-1 activity in muscle or Leydig cells, supporting broader endocrine research.

Benefits for Laboratory Research (GH secretagogue peptides)

• Facilitates dual-pathway GH stimulation studies
• Supports IGF-1 signaling research
• Provides a tool for synergistic growth hormone release experiments
• Ideal for pituitary cell function and receptor interaction studies

Chemical Profile

• Sermorelin: GRF 1-29 NH₂, Molecular Weight 93 g/mol, Formula C₁₄₉H₂₄₆N₄₄O₄₂S
• GHRP-2: Pralmorelin, Molecular Weight 97 g/mol, Formula C₄₅H₅₅N₉O₆